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Status Product Owner Review
Categories Medication Management
Created by Guest
Created on Nov 9, 2022

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Creatinine Clearance Equation

Can the equation in CPSI be revamped to take the the following into consideration so that the patient's clearance in CPSI is their actual clearance?


CREATININE CLEARANCE METHODS

Cockcroft and Gault equation utilizing the tbw (Total body weight) to calculate an estimated CrCL

Cockcroft and Gault equation:
CrCl = [(140 - age) x TBW] / (Scr x 72) (x 0.85 for females)

Cockcroft and Gault equation utilizing the ibw (Ideal body weight) to calculate an estimated creatinine clearance

Cockcroft and Gault equation:
CrCl = [(140 - age) x IBW] / (Scr x 72) (x 0.85 for females)
Note: if the ABW (actual body weight) is less than the IBW use the
actual body weight for calculating the CRCL.

Estimate Ideal body weight in (kg)
Males: IBW = 50 kg + 2.3 kg for each inch over 5 feet.
Females: IBW = 45.5 kg + 2.3 kg for each inch over 5 feet.

Cockcroft and Gault equation utilizing the adjusted body weight to calculate an estimated creatinine clearance.

CrCl = [(140 - age) x AjBW] / (Scr x 72)

Note: (Multiply result by 0.85 for females)
AjBW = adjusted body weight:
AjBW = IBW + 0.4( ABW - IBW)

Estimated IBW:
Males: IBW = 50 kg + 2.3 kg for each inch over 5 feet.
Females: IBW = 45.5 kg + 2.3 kg for each inch over 5 feet.

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  • Guest
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    |     Nov 10, 2022

    You're going to need to spell out to them when to use adjusted body weight vs total body weight, is there a set rule I don't remember specifically but I think it's 30% over IBW use ABW? If they are to build an algorithm to slot profiles into correct equation cascades they need to know these things. They are just programmers not pharmacists.